au sommaire


    1. Mueller PPPP, Hinnebusch AGAG: Multiple Upstream AUG CodonsCodons Mediate Translational Control OF GCN4. Cell 1986, 45:201-207.
    2. Yun DF, Laz TM, Clements JM, Sherman F: mRNA sequences influencing translation and the selection of AUG initiator codons in th yeast Saccharomyces cerevisiaeSaccharomyces cerevisiae. mol. microbiol 1996, 19:1225-1239.
    3. Ivanov IPIP, Simin K, Letsou A, Atkins JF, Gesteland RF: The Drosophila gene for antizyme requires ribosomal frameshifting for expression and contains an intronic gene for snRNP Sm D3 on the opposite strand. Mol Cell Biol 1998, 18:1553-1561.
    4. Major LL, Poole ES, Dalphin ME, Mannering SA, Tate WP: Is the in-frame termination signal of the Escherichia coliEscherichia coli release factor-2 frameshift site weakened by a particularly poor context? Nucleic Acids Res 1996, 24:2673-2678.
    5. Namy O, Duchateau-Nguyen G, Rousset JP: Translational readthrough of the PDE2 stop codon modulates cAMP levels in Saccharomyces cerevisiae. Mol Microbiol 2002, 43:641-652.
    6. Zavialov AV, Buckingham RH, Ehrenberg M: A posttermination ribosomal complex is the guanineguanine nucleotide exchange factor for peptide release factor RF3. Cell 2001, 107:115-124.
    7. Brown CM, Stockwell PA, Trotman CN, Tate WP: Sequence analysis suggests that tetra-nucleotides signal the termination of protein synthesis in eukaryotes. Nucleic Acids Res 1990, 18:6339-6345.
    8. Namy O, Hatin I, Rousset JP: Impact of the six nucleotides downstream of the stop codon on translation termination. EMBO Rep 2001, 2:787-793.
    9. Skuzeski JM, Nichols LM, Gesteland RF, Atkins JF: The signal for a leaky UAG stop codon in several plant viruses includes the two downstream codons. J Mol Biol 1991, 218:365-373.
    10. Eustice DC, Wilhelm JM: Fidelity of the eukaryotic codon-anticodon interaction: interference by aminoglycosideaminoglycoside antibiotics. Biochemistry 1984, 23:1462-1467.
    11. Howard M, Frizzell RA, Bedwell DM: Aminoglycoside antibiotics restore CFTRCFTR function by overcoming premature stop mutations. Nat Med 1996, 2:467-469.
    12. Bedwell DM, Kaenjak A, Benos DJDJ, Bebok Z, Bubien JK, Hong J, Tousson A, Clancy JP, Sorscher EJEJ: Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line. Nat Med 1997, 3:1280-1284.
    13. Keeling KM, Bedwell DM: Clinically relevant aminoglycosides can suppress disease-associated premature stop mutations in the IDUA and P53P53 cDNAs in a mammalian translation system. J Mol Med 2002, 80:367-376.
    14. Howard MT, Shirts BH, Petros LM, Flanigan KM, Gesteland RF, Atkins JF: Sequence specificity of aminoglycoside-induced stop condon readthrough: potential implications for treatment of Duchenne muscular dystrophy. Ann Neurol 2000, 48:164-169.
    15. Krawczak M, Ball EV, Fenton I, Stenson PD, Abeysinghe S, Thomas N, Cooper DN: Human gene mutation database-a biomedical information and research resource. Hum Mutat 2000, 15:45-51.
    16. Vines DJ, Warburton MJ: Classical late infantile neuronal ceroid lipofuscinosis fibroblasts are deficient in lysosomal tripeptidyl peptidasepeptidase I. FEBS Lett 1999, 443:131-135.
    17. Sleat DE, Sohar I, Gin RM, Lobel P: Aminoglycoside-mediated suppression of nonsense mutations in late infantile neuronal ceroid lipofuscinosis. Europ J Paediatr Neurol 2001, 5:57-62.
    18. Barton-Davis ER, Cordier L, Shoturma DI, Leland SE, Sweeney HL: Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice. J Clin Invest 1999, 104:375-381.
    19. Clancy JP, Bebok Z, Ruiz F, King C, Jones J, Walker L, Greer H, Hong J, Wing L, Macaluso M, Lyrene R, Sorscher EJ, Bedwell DM: Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis. Am J Respir Crit Care Med 2001, 163:1683-1692.
    20. Wagner KR, Hamed S, Hadley DW, Gropman AL, Burstein AH, Escolar DM, Hoffman EP, Fischbeck KH: Gentamicin treatment of Duchenne and Becker muscular dystrophy due to nonsense mutations. Ann Neurol 2001, 49:706-711.
    21. Thompson J, O'Connor M, Mills J, Dahlberg A: The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivoin vivo. J Mol Biol 2002, 322:273.